On February 1, 2018 Oncolytics Biotech Inc. (TSX: ONC) (OTCQX: ONCYF), a biotech company developing REOLYSIN, also known as pelareorep, an intravenously delivered immuno-oncolytic virus that activates the innate and adaptive immune systems to turn "cold" tumors "hot", reported that it will host a conference call to discuss the current treatment paradigm of metastatic breast cancer (mBC) subtypes (Press release, Oncolytics Biotech, FEB 1, 2018, View Source [SID1234523714]). The purpose of the call is to highlight the definitive unmet medical need to improve the overall survival of women with advanced or recurrent hormone receptor positive, HER2 receptor negative metastatic breast cancer, and will also discuss certain preliminary details of the Company’s planned phase 3 registration study in mBC. The conference call will take place on Wednesday, February 7, 2018 at 8:30 a.m. ET.
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"In recent years, we’ve seen meaningful advances in clinical studies targeting the HR+/HER2- patient population in the adjuvant setting, but only minor advancements for patients who have failed one or two prior chemotherapy regimens in the metastatic setting," said Andres Gutierrez, Chief Medical Officer of Oncolytics Biotech. "This is a significant patient population that many seem to perceive as having alternatives due to advancements in adjuvant chemotherapy and endocrine therapy, but these advancements have delivered only marginal effects in these HR+/HER2- metastatic breast cancer patients whose current options are merely palliative single-agent regimens that add no survival advantage."
Dr. Matt Coffey, President and CEO, and Dr. Andres Gutierrez, Chief Medical Officer, will discuss the planned phase 3 study design and timeline, followed by comments from Key Opinion Leader Dr. Aleix Prat. Dr. Prat will highlight why the results from Oncolytics’ phase 2 IND 213 in mBC are so meaningful, what the current treatment paradigm is for these patients receiving second and third line chemotherapy and why REOLYSIN could be an important advancement in providing an overall survival benefit to these patients. Following the call, all three speakers will field questions from Research Analysts and Institutional Investors.
Dr. Aleix Prat is the Head of the Medical Oncology of Hospital Clínic of Barcelona, Associate Professor of the University of Barcelona and the Head of the Translational Genomics and Targeted Therapeutics in Solid Tumors Group at August Pi i Sunyer Biomedical Research Institute (IDIBAPS). Dr. Prat designs and leads clinical trials of novel drugs and approaches, and is currently the scientific coordinator of SOLTI, a Spanish breast cancer cooperative group. He has recently been named as a Member of Executive Committee of The Breast International Group (BIG), an international non-profit organisation that includes more than 56 cooperative groups from around the world, more than 10,000 experts and it is linked to more than 3,000 hospitals. Dr. Prat received the International Prize for Breast Cancer Research (Padova, Italy) for his scientific discoveries regarding the characterization and clinical value of the intrinsic subtypes.
Webcast and Conference Call
Oncolytics management will host a conference call with a question and answer session for Analysts and Institutional Investors on Wednesday, February 7, 2018 at 8:30 am ET. The live call may be accessed by dialing 877-407-0839 for callers in North America and overseas callers can access by dialing 201-689-8863. A replay of this call will be available approximately two hours after the call is ended at 877-660-6853 for
North American callers and 201-612-7415 for overseas callers using the replay code 13675935 and will be available for two weeks.
A live audio webcast of the call will be accessible on the Investor Relations page of Oncolytics’ website at www.oncolyticsbiotech.com and will be archived for six months.