On February 18, 2020 Shattuck Labs, Inc. ("Shattuck"), a clinical-stage biotechnology company advancing its proprietary Agonist Redirected Checkpoint (ARC) platform to develop a novel class of biologic medicines for the treatment of cancer and other diseases, reported the appointment of Shattuck’s Chief Scientific Officer and Co-founder, Taylor Schreiber, M.D., Ph.D., to Chief Executive Officer (Press release, Shattuck Labs, FEB 18, 2020, View Source [SID1234554455]). Dr. Schreiber succeeds Josiah Hornblower, who will continue to work with and advise the Company in his role as Executive Chairman of the Board of Directors.
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"I am grateful to have this opportunity to serve as CEO of Shattuck and build upon the tremendous foundation set by Josiah. It is an exciting time for the Company, and the initial Phase 1 clinical trial data from our lead program, SL-279252 (PD1-Fc-OX40L), partnered with Takeda, indicates that ARCs may have unlocked an important class of immune activating receptors," said Taylor Schreiber, M.D., Ph.D. "With several hundred therapeutic candidates derived from the ARC platform technology, Shattuck is poised to rapidly advance product candidates with best-in-class potential toward virtually any target in immuno-oncology which is clinically de-risked by traditional antibody modalities."
"It has been a privilege to lead this incredible team through the foundational stages of developing potentially transformative biologics," said Josiah Hornblower. "As the lead inventor of our first-in-class ARC platform technology, Taylor is well-suited to lead the Company through this next phase of growth. His strong scientific background, passion for the Shattuck vision, and dedication to helping patients will be invaluable as Shattuck achieves clinical proof of concept and demonstrates the disruptive potential of ARC therapeutics as compared to traditional antibody therapies."
Dr. Schreiber co-founded Shattuck in 2016 and previously served as the Chief Scientific Officer. Prior to Shattuck, he co-invented several technologies, including TNFRSF25 agonist technology developed by Pelican Therapeutics, where he served as Chairman of the Scientific Advisory Board. He received his M.D. and Ph.D. degrees from the Sheila and David Fuente Program in Cancer Biology at the University of Miami Miller School of Medicine. He received his B.A. in Biology from Bucknell University.